Exercise no. 311 Netarsudil (RHOKIINSA°) or netarsudil + latanoprost (ROCLANDA°) in chronic glaucoma

Elevated intraocular pressure is a risk factor for chronic open-angle glaucoma, i.e. atrophy of the optic nerve, with progressive visual field loss that can culminate in blindness. Ocular hypertension is conventionally defined as an intraocular pressure greater than 21 mmHg. When intraocular pressure is too high, a first-choice option is to administer eye drops containing the beta-blocker timolol. Eye drops containing the prostaglandin F2alpha analogue latanoprost are an alternative: they lower intraocular pressure slightly more than timolol eye drops, but have more adverse effects. It is sometimes useful to combine timolol and latanoprost when the reduction in intraocular pressure achieved with monotherapy is considered insufficient.