Prescrire's sales representatives (reps) monitoring network was created in 1991 at the initiative of a group of subscribers. For the last 15 years, members of the Network have compared sales reps' claims with the information contained in the summaries of product characteristics.

A variety of methodological precautions were taken to minimise the biases inherent in any 'sentinel' type of observational system. Results have been remarkably consistent over the years.

Sales reps highlight the efficacy of the drugs they present, often for unapproved as well as approved indications. In contrast, adverse effects are not mentioned in three-quarters of visits.

Participation in the Network requires monitors to become better informed about the drugs that are being promoted in order to decipher reps' claims. After a few months, many Network observers decide they no longer want to see sales reps, and opt instead for reliable and independent sources of information.

Similar conclusions have been reached by monitoring networks in other countries. Internationally, a growing movement exists of healthcare professionals who have removed themselves from the sphere of influence of pharmaceutical companies.

Prescrire's sales reps monitoring network ceased its sentinel observational work earlier this year. New research and new actions are planned, focusing on other types of promotion aimed at both healthcare professionals and the public.

©la revue Prescrire 1er août 2006
Prescrire International 2006 ; 15 (84) : 154-159.